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EVENT DESCRIPTION  
 
Event Type:  Workshop (This is an NIH Science event)
 
Title:  Pathways to Prevention Workshop: Appropriate Use of Drug Therapies for Osteoporotic Fracture Prevention
 
Description:  About Osteoporotic Fractures
More than 10 million people in the United States have osteoporosis1, a skeletal disorder that causes bones to become weak and fragile as a result of low bone mass. The condition makes people more susceptible to fractures, which can impair their ability to live independently and even threaten their lives2. The social and economic burden of osteoporotic fractures is substantial3. Reducing osteoporosis prevalence and hip fracture incidence are among the major objectives of Healthy People 2020, the U.S. Department of Health & Human Services’ national health promotion and disease prevention initiative.

Lifestyle changes—including getting adequate nutrition and regular exercise, quitting tobacco use, limiting alcohol use, and preventing falls—can help reduce a person’s risk of osteoporotic fractures. However, medications may be prescribed to prevent fractures if a person has very low bone mineral density or has experienced a prior fragility fracture.

The U.S. Food and Drug Administration has approved several types of drugs to prevent osteoporotic fractures. Clinical guidelines by various medical organizations recommend bisphosphonates (BPs) as a first line of treatment for most people who have osteoporosis. BPs are effective for short-term use (up to 3–5 years) by people who are at high risk of fracture. However, the benefits and risks of longer-term treatment are less clear. Reports of rare but serious adverse events such as atypical femoral fractures and osteonecrosis (death of cells) of the jaw have raised questions about the safety of osteoporosis drug use, especially in people who use the drugs for more than 3–5 years or who had a low risk of fracture when they began treatment.

Research Challenges
There is a gap in scientific data about the appropriate long-term use of many osteoporosis drugs. There are uncertainties about which people will benefit or may be harmed if they take the drugs long-term. Public concern about these an
 
Series Name:  Pathways to Prevention Workshop Program
 
Event URL:  https://prevention.nih.gov/p2p-workshop/2018/osteoporotic-fracture-prevention
 
Videocast:  Event will be videocast LIVE on the Web
 
Videocast URL:  http://videocast.nih.gov
  Event will be available in the videocast ARCHIVE
 
Special Instructions:  Reservations or registration required for this event
 
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EVENT DATE/TIME  
 
Date/Time: 
Tuesday, October 30, 2018   8:30am - 5:30pm Add To Outlook Calendar     Add To iCal Calendar     Add To Entourage Calendar
Wednesday, October 31, 2018   8:30am - 1:00pm Add To Outlook Calendar     Add To iCal Calendar     Add To Entourage Calendar
 
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EVENT SPEAKER(S)  
 
Name:   Multiple Speakers
 

EVENT SPONSOR(S)  
 
Organization(s):  NIH ODP, NIA, and NIAMS
 

EVENT LOCATION  
 
Location:  On the main NIH Campus
Building:  Building 45 (Natcher Building)
 
Street Address:  45 Center Drive
City:  Bethesda
State:  Maryland
Zip Code:  20892
 

EVENT CONTACT(S)  
 
Name:   Deborah Langer
E-mail:   langerdh@od.nih.gov
Phone:   301-827-5575
 
 
 
 
 
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