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Event Type:  Lecture (This is an NIH Science event)
Title:  Using Old Antibiotics to Find New Ones: Induction of Cryptic Secondary Metabolites by Cytotoxic Molecules
Description:  Microbial secondary metabolites serve as a dominant source of pharmaceutical compounds and
comprise some of our most celebrated cures. Recent studies, however, have been plagued by
the frequent rediscovery of old molecules. The underlying reason is that the vast majority of secondary metabolite biosynthetic genes clusters in a given bacterium are not significantly expressed, when cultured under standard laboratory conditions. In combination with emerging profiling methodologies, our efforts are beginning to provide a thorough picture of the secondary metabolomes of bacteria and their chemogenetic modulation by cytotoxic small molecules.
Series Name:  Chemistry Intrest Group
Videocast:  Event will not be videocast
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Wednesday, November 01, 2017   11:00am - 12:00pm Add To Outlook Calendar     Add To iCal Calendar     Add To Entourage Calendar
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Name:   Mohammad R. Seyedsayamdost
Title:   Assistant Professor, Department of Chemistry
Organization:   Princeton University

Organization(s):  [NIH] Chemistry Interest Group

Location:  On the main NIH Campus
Building:  Bulding 50
Room:  Room 1227/1233

Name:   Carole Bewley
Phone:   301-594-5187
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