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Event Type:  Lecture (This is an NIH Science event)
Title:  The IL-23-Th17 Immune Axis: From Bench to Bedside
Description:  Following the discovery of IL-23-dependent T cell immunity, the past decade has witnessed a major revision of the T-helper subset paradigm and substantial progress has been made in deciphering the molecular mechanisms of T cell lineage commitment and function. Our recent work focused on the transcriptional control of Th17 cell development, as well as the protective versus pathogenic roles of IL-17 and IL-22 in mucosal tissues. I will discuss the concept of immune ‘counter-regulation’ during organ-specific tissue inflammation. I will also highlight recent clinical data demonstrating that neutralization of IL-17 and IL-23 are remarkably effective for treating immune-mediated inflammatory diseases.
Series Name:  Immunology Interest Group Seminar Series
Event URL:
Videocast:  Event will be videocast LIVE on the Web
Videocast URL:
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Wednesday, October 11, 2017   4:15pm - 5:15pm Add To Outlook Calendar     Add To iCal Calendar     Add To Entourage Calendar
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Name:   Daniel Cua
Title:   Group Leader, Immunology Discovery and Immuno-Oncology Discovery
Organization:   Merck Research Laboratories

Organization(s):  [NIH] Immunology Interest Group

Location:  On the main NIH Campus
Building:  Building 10, Lipsett auditorium

Name:   Niki Moutsopoulos
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