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EVENT DESCRIPTION  
 
Event Type:  Lecture (This is an NIH Science event)
 
Title:  The IL-23-Th17 Immune Axis: From Bench to Bedside
 
Description:  Following the discovery of IL-23-dependent T cell immunity, the past decade has witnessed a major revision of the T-helper subset paradigm and substantial progress has been made in deciphering the molecular mechanisms of T cell lineage commitment and function. Our recent work focused on the transcriptional control of Th17 cell development, as well as the protective versus pathogenic roles of IL-17 and IL-22 in mucosal tissues. I will discuss the concept of immune ‘counter-regulation’ during organ-specific tissue inflammation. I will also highlight recent clinical data demonstrating that neutralization of IL-17 and IL-23 are remarkably effective for treating immune-mediated inflammatory diseases.
 
Series Name:  Immunology Interest Group Seminar Series
 
Event URL:  https://ecollab.niaid.nih.gov/sites/IIG/Lists/Immunology%20Interest%20group%20Seminar%20Series/AllIt
 
Videocast:  Event will be videocast LIVE on the Web
 
Videocast URL:  http://videocast.nih.gov
 
Special Instructions:  To arrange sign language interpretation for an event go to the Office
of Research Services (ORS) Interpreting Service Requests web page.
 

EVENT DATE/TIME  
 
Date/Time: 
Wednesday, October 11, 2017   4:15pm - 5:15pm Add To Outlook Calendar     Add To iCal Calendar     Add To Entourage Calendar
 
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EVENT SPEAKER(S)  
 
Name:   Daniel Cua
Title:   Group Leader, Immunology Discovery and Immuno-Oncology Discovery
Organization:   Merck Research Laboratories
 

EVENT SPONSOR(S)  
 
Organization(s):  [NIH] Immunology Interest Group
 

EVENT LOCATION  
 
Location:  On the main NIH Campus
Building:  Building 10, Lipsett auditorium
 
 

EVENT CONTACT(S)  
 
Name:   Niki Moutsopoulos
E-mail:   nmoutsop@mail.nih.gov
 
 
 
 
 
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