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EVENT DESCRIPTION  
 
Event Type:  Lecture (This is an NIH Science event)
 
Title:  Cellular Communication: How Cells Control Who they’re Talking to and What they’re Saying
 
Description:  In multicellular organisms, a handful of intercellular communication pathways, such as Notch and BMP, play an outside role in controlling cell fate decisions. While we have much information about the specific molecules and interactions that comprise these pathways, we often understand little about the particular signal processing behaviors each pathway provides. We have been developing a ‘build-to-understand’ approach to this problem, reconstructing or re-wiring these pathways using synthetic biology approaches, and analyzing their dynamic behaviors at the level of individual cells. For his lecture, Dr. Elowitz will focus on a particular architectural feature in which a pathway uses multiple distinct ligand and receptor variants that interact promiscuously with one another. New results suggest how this apparent redundancy can, counterintuitively, allow control of signal specificity (“who talks to whom”) and target program (“message”). Dr. Elowitz will also discuss a new synthetic approach termed MEMOIR that should enable cells to record their own signaling histories over longer timescales.
 
Series Name:  Wednesday Afternoon Lecture Series
 
Event URL:  https://oir.nih.gov/wals
 
Videocast:  Event will be videocast LIVE on the Web
 
Videocast URL:  http://videocast.nih.gov
  Event will be available in the videocast ARCHIVE
 
Special Instructions:  Continuing Medical Education (CME) event
 
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EVENT DATE/TIME  
 
Date/Time: 
Wednesday, December 06, 2017   3:00pm - 4:00pm Add To Outlook Calendar     Add To iCal Calendar     Add To Entourage Calendar
 
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EVENT SPEAKER(S)  
 
Name:   Professor Michael Elowitz
Title:   Professor of Biology, Bioengineering and Applied Physics
Organization:   California Institute of Technology
 

EVENT SPONSOR(S)  
 
Organization(s):  [NIH] Office of the Director (OD)
 

EVENT LOCATION  
 
Location:  On the main NIH Campus
Building:  10
Room:  Masur Auditorium
 
 

EVENT CONTACT(S)  
 
Name:   Jacqueline Roberts
E-mail:   robertsjm@od.nih.gov
Phone:   301-594-6747
 
 
 
 
 
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