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Event Type:  Seminar (This is an NIH Science event)
Title:  Biosensing and Theranostic Systems Based on AIEgens
Description:  Biography: Ben Zhong Tang is Stephen K. C. Cheong Professor of Science and Chair Professor of Chemistry and Biomedical Engineering at The Hong Kong University of Science and Technology. His research interests include macromolecular chemistry, materials science, and biomedical theranostics. He is spearheading the research on aggregation-induced emission (AIE). Tang received B.S. and Ph.D. degrees from South China University of Technology and Kyoto University, respectively. He conducted postdoctoral research at University of Toronto. He joined HKUST as an assistant professor in 1994 and was promoted to chair professor in 2008. He was elected to the Chinese Academy of Sciences and the Royal Society of Chemistry in 2009 and 2013, respectively.

Abstract: Traditional p-conjugated fluorophors tend to aggregate with light emission quenching which is known as aggregation-caused quenching. We have observed an opposite phenomenon termed “aggregation-induced emission” (AIE) and identified the restriction of intramolecular rotation as the main reason for the AIE effect. AIE luminogens (AIEgens) permit the use of dye solutions with any concentration for bioassays and enable the development of ‘‘turn-on’’ biosensors by taking the advantage of luminogenic aggregation. Many AIE-based biosensing systems with high sensitivity and accuracy for detecting carbohydrates, lipids, amino acids, proteins, enzymes and nucleic acids have been developed. AIEgens also provide a multifunctional platform that allows simultaneous diagnosis and therapy, which now is known as theranostics. Several theranostic AIE systems have been exploited and proven to be powerful, such as fluorescence image-guided photodynamic therapy, fluorescence image-guided chemotherapy, fluorescence image-guided surgery, photoacoustic image-guided photothermal therapy, fluorescence and photoacoustic dual imaging, and fluorescence and magnetic resonance dual imaging.
Series Name:  NANO SIG Seminar Series
Videocast:  Event will not be videocast
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Monday, August 21, 2017   11:00am - 12:00pm Add To Outlook Calendar     Add To iCal Calendar     Add To Entourage Calendar
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Name:   Ben Zhong Tang
Title:   Stephen K. C. Cheong Professor of Science and Chair Professor of Chemistry
Organization:   Hong Kong University of Science and Technology

Organization(s):  [NIH] National Institute of Biomedical Imaging and Bioengineering (NIBIB)

Location:  On the main NIH Campus
Building:  35
Room:  2G600
Street Address:  35A Convent Dr
City:  Bethesda
State:  Maryland
Zip Code:  20892

Name:   Shawn Chen
Phone:   3014514246
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