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Event Type:  Seminar (This is an NIH Science event)
Title:  Harnessing Exocytosis of Nanoparticles to Improve Cancer Nanomedicine
Description:  Biography: Ji-Ho Park is Associate Professor of Bio and Brain Engineering at Korea Advanced Institute of Science and Technology (KAIST) South Korea. He holds Affiliate appointments in the Graduate School of Medical Science and Engineering, and the Institute of Health Science and Technology at KAIST. He received a B.S. degree in Materials Science and a M.S. degree in Medical Science from Yonsei University (South Korea). He then moved to the USA and received his Ph.D. degree in Materials Science from University of California, San Diego under the direction of Professor Michael Sailor in 2009. He joined the faculty in the Department of Bio and Brain Engineering at KAIST in 2010, after postdoctoral studies at University of California, Berkeley under Professor Peidong Yang. He was promoted to Associate Professor in 2015. He is the recipient of Young Investigator Award from the Korean Society of Medical and Biological Engineering.
Abstract: Synthetic nanoparticles engineered for systemic administration into the body have great potential to overcome current limitations of cancer therapies. Despite significant effort to enhance their targeting capability, an unfavorable tumor microenvironment results in poor penetration and uneven distribution of targeted nanoparticles that reach the tumor, reducing the overall therapeutic efficacy. In this talk, I will discuss our recent efforts to harness exocytosis of nanoparticles for improving cancer nanomedicine. Our efforts span understanding of endocytosis and exocytosis patterns of nanoparticles in tumor cells and macrophages, and development of new delivery systems in which exocytosis of nanoparticles in the tumor microenvironment can be leveraged to improve tissue penetration and therapeutic efficacy.
Series Name:  NANO SIG Seminar Series
Videocast:  Event will not be videocast
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Friday, August 11, 2017   11:00am - 12:00pm Add To Outlook Calendar     Add To iCal Calendar     Add To Entourage Calendar
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Name:   Ji Ho Park
Title:   Associate Professor
Organization:   KAIST
Country:   Korea

Organization(s):  [NIH] National Institute of Biomedical Imaging and Bioengineering (NIBIB)

Location:  On the main NIH Campus
Building:  35
Room:  2G600
Street Address:  35A Convent Dr
City:  Bethesda
State:  Maryland
Zip Code:  20892

Name:   Shawn Chen
Phone:   3014514246
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