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Event Type:  Seminar (This is an NIH Science event)
Annual Lecture:  Other
Title:  Hematopoietic Stem Cells Aging – Mechanisms, Consequences and Interventions
Description:  The Trans-NIH GeroScience Interest Group (GSIG), cordially invites you to its summer seminar, featuring Dr. Emmanuelle Passegué. Dr. Passegue is a Professor in the Department of Genetics and Development at the Columbia University Medical Center and Director of the Columbia Stem Cell Initiative (CSCI) in New York. She is widely recognized for her expertise on hematopoietic stem cell (HSC) biology. Her research over the past 10-years has focused on understanding the cellular and molecular processes controlling HSC activity during homeostasis, and addressing how these regulations are changed in myeloid malignancies and physiological aging. Her laboratory employs a variety of cross-disciplinary approaches using mouse models and human patient samples to identify genetic and/or molecular pathways as therapeutic targets to treat human diseases. Current projects investigate the role of apoptosis, autophagy, immune regulations, DNA repair mechanisms, and changes in the bone marrow niche microenvironment in HSC function in normal, stress, leukemic and aging conditions.

We hope you’ll be able to join us in person to hear this engaging speaker and interesting story. Dr. Passegué will also be available before and after the seminar – anyone interested in meeting with her should contact me two weeks before the seminar at or 301/827-4013.

The GSIG was created to discuss and explore the complex relationships between the biology of aging and the biology of diseases and conditions that are of interest to various institutes and centers across the NIH. If you are interested in learning more, please visit the GSIG web site (

The seminar will be videocast at and archived in the GSIG web site.

Sign Language Interpreters will be provided. Individuals with disabilities who need reasonable accommodation to participate in this event should contact Dr. Francesca Macch
Series Name:  GSIG Seminars
Event URL:
Videocast:  Event will be videocast LIVE on the Web
Videocast URL:
  Event will be available in the videocast ARCHIVE
Special Instructions:  To arrange sign language interpretation for an event go to the Office
of Research Services (ORS) Interpreting Service Requests web page.

Thursday, July 13, 2017   12:00pm - 1:00pm Add To Outlook Calendar     Add To iCal Calendar     Add To Entourage Calendar
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Name:   Dr. Emmanuelle Passegué
Title:   Prof in Dept of Genetics & Dev & Director of CSCI
Organization:   Columbia University Medical Center
City/Province:   New York
State:   New York

Organization(s):  [NIH] National Institute on Aging (NIA); Alliance for Aging Research

Location:  On the main NIH Campus
Building:  Building 49
Room:  Room 1A51/1A59
Street Address:  49 Convent Drive
City:  Bethesda
State:  Maryland
Zip Code:  20892

Name:   Francesca Macchiarini, M.S., Ph.D.
Phone:   301-827-4013
Fax:   301-402-0010
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