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EVENT DESCRIPTION  
 
Event Type:  Seminar (This is an NIH Science event)
 
Title:  Hijacking of Immune Regulatory Mechanisms in Lymphoid Malignancies
 
Description:  Signalling through the B cell receptor (BCR) is central to the development and maintenance of B cells. In light of the numerous proliferative and survival pathways activated downstream of the BCR, it comes as no surprise that malignant B cells would co-opt this receptor to promote their own growth and survival. However, direct evidence for BCR signalling in human lymphoma has only come to light recently. Roles for antigen-dependent and antigen-independent, or tonic, BCR signalling have now been described for several different lymphoma subtypes. Furthermore, correlative data implicate antigen-dependent BCR signalling in many other forms of lymphoma. A host of therapeutic agents targeting effectors of the BCR signalling pathway are now in clinical trials and have shown initial success against multiple forms of lymphoma.
 
Series Name:  Immunology Interest Group Seminar Series
 
Videocast:  Event will be videocast LIVE on the Web
 
Videocast URL:  http://videocast.nih.gov
 
Special Instructions:  To arrange sign language interpretation for an event go to the Office
of Research Services (ORS) Interpreting Service Requests web page.
 

EVENT DATE/TIME  
 
Date/Time: 
Wednesday, April 19, 2017   4:15pm - 5:30pm Add To Outlook Calendar     Add To iCal Calendar     Add To Entourage Calendar
 
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EVENT SPEAKER(S)  
 
Name:   Dr. Louis Staudt
Title:   Director, Center for Cancer Genomics
Organization:   National Cancer Institute
City/Province:   Bethesda
State:   Maryland
Country:   United States
 

EVENT SPONSOR(S)  
 
Organization(s):  [NIH] Immunology Interest Group
 

EVENT LOCATION  
 
Location:  On the main NIH Campus
Building:  Building 10
Room:  Lipsett Amphitheater
 
Street Address:  9000 Rockville Pike
City:  Bethesda
State:  Maryland
Zip Code:  20892
 

EVENT CONTACT(S)  
 
Name:   Vanja Lazarevic
E-mail:   lazarevicv@mail.nih.gov
Phone:   3014516882
 
 
 
 
 
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